Where is Your Brain with Arthur Carmazzi – Brain Processing Genes

Where is Your Brain with Arthur Carmazzi – Brain Processing Genes

Arthur Carmazzi takes us into the first steps in Brain Genetics of how our brain’s Ambiguity Relief processes are created in the Prefrontal Cortex and HOW your brain gets clarity. Watch the video and read more about the molecular biology behind the Colored Brain Psychometric tool bellow.


The COMT gene affects the Ambiguity Relief process in the Prefrontal Cortex. The COMT gene long and short alleles provide instructions for making specific enzymes that affect Dopamine and Norepinephrine neurotransmitters in this part of the brain. The longer form of an enzyme, called catechol-O-methyltransferase (MB-COMT) is important in the prefrontal cortex, which organizes and coordinates information from other parts of the brain. It is also responsible for planning, inhibition of behaviors, abstract thinking, emotion, and problem solving. The prefrontal cortex requires signalling by dopamine (DA) and norepinephrine (NE), MB-COMT helps to maintain levels of dopamine and norepinephrine that support that and activate special receptors also created by DRD genes. This regulation activity has an essential role in differentiation of focused attention (connected) vs inhibition of distractions while paying attention (not connected) as well as the need or disregard for structure or details in organizing information.

Low doses of DA in the Prefrontal Cortex enhance the spatial tuning associated with more abstract and intuitive processing while higher levels of DA produce more selective memory activity associated with planning and structure.

Lower NE was found to be associated with a more connected process where information and emotion are interrelated. While higher levels of NE actively needed to connect information and emotion.

But it was the combinations of NE and DA that was associated with the various Ambiguity Relief processes observed. Lower NE combined with low DA was identified as having an intuitive internally connected reflective process, while highly detailed individuals had also had low NE but with higher levels of DA showing a relational connected process. Similarly higher NE levels with lower DA showed a more abstract, disconnected, Chaotic process, while higher NE and DA exhibited an structured Linier process that required active connection.

How does this apply to team leadership development?

The Colored Brain psychometric profiling tool, unveils the brains genetic Ambiguity Relief processes. When faced with a decision, a problem, an idea or a task, the brain must first go through a unique process of “Ambiguity Relief”. We have identified four unique processes related to the amounts of neurotransmitters produced by specific genes and made it Simple to use and apply through the Colored Brain model. Colored Brain makes it EASY to understand unique communication requirements that often prevent getting everyone speaking the same language… and helps you CRUSH the barriers to create EASIER, FASTER and MORE EFFECTIVE communication across any group or relationship.

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