Where is Your Brain with Arthur Carmazzi – Brain Process Genes of the Hippocampus

Where is Your Brain with Arthur Carmazzi – Brain Process Genes of the Hippocampus

Episode 4 of WHERE IS YOUR BRAIN, Arthur Carmazzi the genes related to AMBIGUITY RELIEF in the Hippocampus (in a fun and easy to understand way).

The ultimate goal is to understand this brain science to improve relationships, teamwork, and move people to action. Many Psychometric tools incorporate the idea of Ambiguity Relief without realizing it so it is not fully reviled.

But the only psychometric tool that exclusively reviles Ambiguity Relief is Colored Brain. Colored Brain identifies Ambiguity Relief to support team building and team communication… and the leadership to create high performance teams

The SPR gene provides instructions for making and regulation of the monoamines (serotonin, dopamine, norepinephrine, and epinephrine) in the Hippocampus.

Serotonin in the Hippocampus helps translate what a person sees, hears, feels, etc. into meaningful information and is therefore key to Ambiguity Relief, but it is never standalone and requires and affects other neurotransmitters to do it’s work. It is a key component that modulates the responses of neurons to other neurotransmitters. Almost all serotonin receptor subtypes are expressed in hippocampus, which implicates an intricate modulating system. This Implies an integrated connectivity of information which multiple Monoamine receptors and regulation are connected to how information is linked or associated to other information. This affects a process where either everything is connected to existing memory or where nothing is connected and must be connected to achieve Ambiguity Relief. More 5-HT receptors allow more independent ideas and information pockets within dendrite groups while less create more connectivity between information ideas to achieve Ambiguity Relief. Each process is also related to levels of plasticity for processing outcomes.

The CHRNA4 gene]provides instructions for making one part (subunit) of a larger protein called a neuronal nicotinic acetylcholine receptor (nAChR). Cool name huh!

Acetylcholine: this is mostly associated with memory and recall but the translation on information into memory is required before the memory is stored. Acetylcholine is abundant in the brain but, more or less receptors for Acetylcholine determine variances in plasticity of the and connectivity of the brain. More Acetylcholine supports more plasticity. Acetylcholine is also responsible for speed, and while ADHD is usually identified with low Acetylcholine levels which affect concentration, this is not related to the information processing. Increased speed affects multi-tasking and abstract thinking processes but lowers attention to detail and impairs structure, lower speed supports structure and detail oriented processes but reduce spontaneity and plasticity.

While Acetylcholine affects Speed of Processing, the ratio of how you can understand stuff while lots of other stuff is going on, is affected by Norepinephrine and Acetylcholine which makes the brain to make association from weird or non related stuff. So higher levels of NE and ACh process in broader scopes of interpretation like abstract thinking and intuition.


This would imply that within the normal spectrum of operating level, that higher amounts of dopamine support the extra need for structure and detail required to achieve clarity, before taking action. Decreased Serotonin, and dopamine with higher levels of norepinephrine would have a direct relationship to introspective and reflective processing and support stronger empathy, while increased serotonin and dopamine with higher levels norepinephrine in the hippocampus supported action based, abstract, chaotic processes.

…and all this comes back to the practical aspects of the science of Leadership Development and Team Synergy. Using Colored Brain is simple, fortunately, for it to be applied we don’t need to know the science be.


#whereisyourbrain #arthurcarmazzi #directivecommunication #coloredbrain


Check out the First post in the Where is Your Brain series that talks about Ambiguity Relief 

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